Document 0047
 DOCN  M9490047
 TI    Comparison of virulence of Mycobacterium avium complex (MAC) strains
       isolated from AIDS and non-AIDS patients.
 DT    9411
 AU    Reddy VM; Parikh K; Luna-Herrera J; Falkinham JO 3rd; Brown S;
       Gangadharam PR; Mycobacteriology Research Laboratories, University of
       Illinois; College of Medicine at Chicago.
 SO    Microb Pathog. 1994 Feb;16(2):121-30. Unique Identifier : AIDSLINE
       MED/94322658
 AB    Mycobacterium avium complex (MAC) strains from AIDS and non-AIDS
       patients and from the environment were studied for their colony
       morphology and virulence in beige mice. The majority of the MAC isolates
       from AIDS patients, in contrast to those from non-AIDS patients and the
       environment, showed increased virulence. Similarly, the majority of the
       MAC isolates from AIDS patients formed smooth transparent (ST) colonies,
       whereas most of the non-AIDS isolates formed smooth opaque (SO) or
       intermediate (IM) type of colonies. MAC isolates from the same AIDS
       patient obtained at different times were found to be heterogenic with
       respect to serotype, RFLP and glycolipid patterns, suggesting that these
       patients might be infected with more than one strain of MAC.
 DE    Animal  AIDS-Related Opportunistic Infections/*MICROBIOLOGY  Colony
       Count, Microbial  Comparative Study  Female  Genotype  Human  Male  Mice
       Mice, Inbred C57BL  Mycobacterium avium
       Complex/CYTOLOGY/GENETICS/ISOLATION & PURIF/  *PATHOGENICITY
       Mycobacterium avium-intracellulare Infection/*MICROBIOLOGY  Phenotype
       Support, U.S. Gov't, P.H.S.  Virulence  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).